| 产品详情 |
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| Antigenic Specificity | CD264 (TRAIL-R4) |
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| Clone | TRAIL-R4-01 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD264 (TRAIL-R4) Monoclonal Antibody (TRAIL-R4-01), FITC. TRAIL-R4 (CD264, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs to receptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4, however, contains partially truncated death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4). |
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| Immunogen | n/a |
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| Other Names | CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD, TRAIL receptor 4 |
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| Gene, Accession # | Entrez: 8793; Uniprot: Q9UBN6 |
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| Catalog # | MA1-10163 |
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| Price | |
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| Order / More Info | CD264 (TRAIL-R4) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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