| 产品详情 |
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| Antigenic Specificity | BANP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 10 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BANP Polyclonal Antibody. BANP was initially identified as a binding protein to BTG3 in a yeast two-hybrid screen. BANP acts as a tumor suppressor by stabilizing p53 expression and leading to cell cycle arrest. p53 in turn binds to upstream elements of the BANP promoter, thereby forming a feedback loop. BANP is down-regulated in advanced stages of human breast cancer, and its overexpression in breast cancer cell lines inhibits their ability to metastasize by modulating TGF-beta signaling. Furthermore, BANP can modulate NF-kappa-B transactivation and can inhibit tumorigenesis by regulating NF-kappa-B target genes. Recent experiments have shown that BANP can also repress HIV-1 LTR mediated transcription by tethering the LTR matrix attachment |
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| Immunogen | n/a |
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| Other Names | BEND1, SMAR1, SMARBP1; BEN domain-containing protein 1; protein BANP; scaffold/matrix-associated region-1-binding protein |
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| Gene, Accession # | Entrez: 292064, 53325, 54971; Uniprot: Q8N9N5, Q8VBU8 |
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| Catalog # | PA5-21030 |
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| Price | |
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| Order / More Info | BANP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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