| 产品详情 |
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| Antigenic Specificity | BAP1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BAP1 Polyclonal Antibody. BRCA1-associated protein-1,' or BAP1 interacts with the RING finger domain of BRCA1. The N-terminal 240 amino acids of the predicted 729-amino acid human protein show homology to ubiquitin C-terminal hydrolases (UCHs), thiol proteases that catalyze proteolytic processing of ubiquitin. In addition, BAP1 contains an acidic region, a highly charged C-terminal region, and 2 putative nuclear localization signals. BAP1 and BRCA1 associate in vivo and have overlapping subnuclear localization patterns. BAP1 enhances BRCA1-mediated inhibition of breast cancer cell growth. Northern blot analysis indicates that BAP1 is expressed as a 4-kb mRNA in all human tissues tested, with A 4.8-kb transcript expressed exclusively in test |
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| Immunogen | n/a |
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| Other Names | DKFZp686N04275, FLJ35406, FLJ37180, HUCEP-13, KIAA0272, UCHL2, hucep-6 |
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| Gene, Accession # | Entrez: 8314; Uniprot: Q92560 |
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| Catalog # | A302-243A-M |
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| Price | |
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| Order / More Info | BAP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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