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| Antigenic Specificity | MIOS |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MIOS Polyclonal Antibody. As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and GATSL3 (PubMed:25457612, PubMed:27487210). |
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| Immunogen | n/a |
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| Other Names | MIO; Sea4; WD repeat-containing protein mio; H_DJ1159O04.1; WUGSC:H_DJ1159O04.1; missing oocyte, meiosis regulator, homolog |
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| Gene, Accession # | Entrez: 54468; Uniprot: Q9NXC5 |
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| Catalog # | PA5-65713 |
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| Price | |
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| Order / More Info | MIOS Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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