| Edit |   |
| Antigenic Specificity | CDH4 |
| Clone | OTI6H5 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | purified |
| Size | 100 µl |
| Concentration | n/a |
| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CDH4 Monoclonal Antibody (OTI6H5). N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium d |
| Immunogen | n/a |
| Other Names | Cadherin-4; Retinal cadherin; R-cadherin; R-CAD |
| Gene, Accession # | Entrez: 1002; Uniprot: P55283 |
| Catalog # | MA5-26696 |
| Price | |
| Order / More Info | CDH4 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |