| 产品详情 |
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| Antigenic Specificity | Phospho-HPK1 (Ser171) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Dot blot: 1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-HPK1 (Ser171) Polyclonal Antibody. The c-Jun amino-terminal kinases (JNKs)/stress-activated protein kinases (SAPKs) play a crucial role in stress responses in mammalian cells. The mechanism underlying this pathway in the hematopoietic system is unclear, but it is a key in understanding the molecular basis of blood cell differentiation. We have cloned a novel protein kinase, termed hematopoietic progenitor kinase 1 (HPK1), that is expressed predominantly in hematopoietic cells, including early progenitor cells. HPK1 is related distantly to the p21(Cdc42/Rac1)-activated kinase (PAK) and yeast STE20 implicated in the mitogen-activated protein kinase (MAPK) cascade. Expression of HPK1 activates JNK1 specifically, and it elevates strongl |
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| Immunogen | n/a |
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| Other Names | EC 2.7.11.1; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1; Hematopoietic progenitor kinase |
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| Gene, Accession # | Entrez: 11184; Uniprot: Q92918 |
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| Catalog # | PA5-12881 |
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| Price | |
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| Order / More Info | Phospho-HPK1 (Ser171) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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