| 产品详情 |
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| Antigenic Specificity | Phospho-IGF2R (Ser2409) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-IGF2R (Ser2409) Polyclonal Antibody. CD222 (CIMPR, cation-independent mannose 6-phosphate receptor; IGF2 receptor) is a ubiquitously expressed 250 kDa transmembrane protein. No more than 10% of CD222 is present on the cell surface where it serves as a multifunctional receptor. Intracellular (major) fraction of CD222 is involved in transport of newly synthesized lysosomal enzymes modified by mannose 6-phosphate from Golgi apparatus to lysosomes. The cell surface CD222 binds and internalizes exogeneous mannose 6-phosphate-containing ligands. Importantly, CD222 is crutial for internalization and degradation of insulin-like growth factor 2, thus controling cell growth. CD222 also complexes CD87 (urokinase-type plasminogen-activator rece |
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| Immunogen | n/a |
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| Other Names | CD222, CIMPR, M6P-R, MPR1, MPRI, 300 kDa mannose 6-phosphate receptor, CI Man-6-P receptor, CI-MPR, IGF-II receptor, M6P/IGF2 receptor, M6P/IGF2R, IGF2R |
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| Gene, Accession # | Entrez: 16004, 3482; Uniprot: P11717, Q07113 |
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| Catalog # | PA5-37605 |
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| Price | |
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| Order / More Info | Phospho-IGF2R (Ser2409) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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