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| Antigenic Specificity | Phospho-IkB alpha (Ser32, Ser36) |
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| Clone | H.709.9 |
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| Host Species | Mouse |
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| Reactive Species | bovine, canine, guinea pig, human, mouse, nonhuman primate, porcine, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-IkB alpha (Ser32, Ser36) Monoclonal Antibody (H.709.9). IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity. The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol. The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus. A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha. These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses. In humans, the |
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| Immunogen | n/a |
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| Other Names | I-kappa-B-alpha; IkappaBalpha; NF-kappa-B inhibitor alpha; ikB-alpha; major histocompatibility complex enhancer-binding protein MAD3; nuclear factor of kappa light chain gene enhancer in B-cells |
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| Gene, Accession # | Entrez: 100723189, 18035, 25493, 282291, 406188, 4792, 480291; Uniprot: P25963, Q08353, Q63746, Q9Z1E3 |
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| Catalog # | MA5-15224 |
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| Price | |
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| Order / More Info | Phospho-IkB alpha (Ser32, Ser36) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 26506421 |
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