| 产品详情 |
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| Antigenic Specificity | ABRA1 |
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| Clone | ABRA1-01 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1-2 µg/mL, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ABRA1 Monoclonal Antibody (ABRA1-01). ABRA1 (Abraxas), also known as CCDC98, is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation. |
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| Immunogen | n/a |
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| Other Names | UNQ496/PRO1013, ABRA1, CCDC98, FLJ11520, FLJ12642, FLJ13614, BRCA1-A complex subunit Abraxas, abraxas protein, coiled-coil domain containing 98, coiled-coil domain-containing protein 98 |
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| Gene, Accession # | Entrez: 84142; Uniprot: Q6UWZ7 |
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| Catalog # | MA1-10045 |
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| Price | |
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| Order / More Info | ABRA1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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