| 产品详情 |
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| Antigenic Specificity | KDM5B |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:200-1:500, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KDM5B Polyclonal Antibody. KDM5B is a histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. It does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. KDM5B demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. It acts as a transcriptional corepressor for FOXG1B and PAX9. It favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, KDM5B may act as a tumor suppressor for melanoma. |
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| Immunogen | n/a |
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| Other Names | RBBP2H1A, PLU1, PLU-1, CT31, lysine K-specific demethylase 5B, JARID1B, PUT1 |
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| Gene, Accession # | Entrez: 10765; Uniprot: Q9UGL1 |
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| Catalog # | PA5-55535 |
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| Price | |
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| Order / More Info | KDM5B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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