| 产品详情 |
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| Antigenic Specificity | MiTF |
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| Clone | 21D1418 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 0.1-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MiTF Monoclonal Antibody (21D1418). Microphthalmia-associated bHLH-LZ transcription factor (MITF) is a positively acting transcription factor containing a transcription activation domain and a bHLH-LZ domain that mediates DNA-binding and dimerization. Both the transcription activation and bHLH-LZ domains are highly conserved in the closely related TFE3, TFEB and TFEC. MITF can form heterodimers in vitro with the above transcription factors, but not with other bHLH-LZ factors such as Myc, Max or USF. MITF is expressed as multiple isoforms, which share common activation and DNA-binding domains, but differ in the amino-terminal region. MITF is targeted by three kinases: GSK-3beta, Map kinase ERK2 and members of the p90 Rsk family of kinases. |
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| Immunogen | n/a |
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| Other Names | MI, WS2, WS2A, bHLHe32, class E basic helix-loop-helix protein 32 |
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| Gene, Accession # | Entrez: 17342, 25094, 4286; Uniprot: O75030, O88368, Q08874 |
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| Catalog # | MA5-16214 |
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| Price | |
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| Order / More Info | MiTF Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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