| 产品详情 |
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| Antigenic Specificity | Coronin 1A |
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| Clone | OTI1A5 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Coronin 1A Monoclonal Antibody (OTI1A5). Highly conserved coronin family of proteins/actin regulators from WD-repeat superfamily were originally identified in Dictyostelium, wherein, coronin deletions were observed to affect actin-dependent processes, such as phagocytosis, cell motility, and cytokinesis. Coronin-1A (Coro1A) belongs to Type I coronins, almost exclusively expressed in hematopoietic lineages, and plays a key role during T lymphocyte activation, migration, survival, and calcium signaling. Moreover, Coronin-1A has been documented to be dispensable for actin-dependent functions in macrophages. Coro1a-deficient mice have reduced peripheral T cells due to both an impaired survival of naive cells and migrational defects. Both CD4+ a |
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| Immunogen | n/a |
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| Other Names | CORO1A; Coronin 1; TACO; p57; CLABP; HCORO1; CLIPINA; Clabp TACO; coronin, actin binding protein, 1A; coronin-1; coronin, actin-binding, 1A; coronin, actin-binding protein, 1A; FLJ41407; MGC117380; |
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| Gene, Accession # | Entrez: 11151; Uniprot: P31146 |
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| Catalog # | MA5-25176 |
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| Price | |
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| Order / More Info | Coronin 1A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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