| 产品详情 |
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| Antigenic Specificity | Phospho-IkB alpha (Tyr42) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-IkB alpha (Tyr42) Polyclonal Antibody. IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity. The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol. The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus. A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha. These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses. In humans, the gene is located o |
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| Immunogen | n/a |
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| Other Names | I kappa B alpha, I kappa B alpha, I(Kappa)B(alpha), I(Kappa)B(alpha), I-kappa-B-alpha, IkappaBalpha, IkB-alpha, IKBA, IKBA, IKBA, IKBalpha, MAD 3, MAD 3, MAD3, Major histocompatibility complex enhancer binding protein MAD3, Major histocompatibility complex enhancer binding protein MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappa-B inhibitor alpha, NFKBI, NFKBI, NFKBIA, NFKBIA, Nuclear factor of kappa light chain gene enhancer in B c |
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| Gene, Accession # | Entrez: 18035, 25493, 4792; Uniprot: P25963, Q63746, Q9Z1E3 |
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| Catalog # | PA5-36825 |
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| Price | |
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| Order / More Info | Phospho-IkB alpha (Tyr42) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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