| 产品详情 |
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| Antigenic Specificity | Phospho-IkB epsilon (Ser18, Ser22) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-IkB epsilon (Ser18, Ser22) Polyclonal Antibody. NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). F |
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| Immunogen | n/a |
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| Other Names | I-kappa-B-epsilon; NF-kappa-B inhibitor epsilon; NF-kappa-BIE; ikB-E; ikB-epsilon; ikappaBepsilon |
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| Gene, Accession # | Entrez: 102155642, 18037, 316241, 4794, 506727; Uniprot: O00221, O54910 |
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| Catalog # | PA5-17532 |
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| Price | |
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| Order / More Info | Phospho-IkB epsilon (Ser18, Ser22) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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