| 产品详情 |
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| Antigenic Specificity | GANP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GANP Polyclonal Antibody. GANP (germinal center-associated nuclear protein) is up-regulated selectively in germinal centers and carries an MCM-binding domain in the carboxyl-terminal side. It was found that a region (from 414 to 550 aa) in GANP molecule that is slightly similar to the known DNA-primase component p49. The recombinant GANP fragment covering this region synthesizes RNA primers for extension by DNA polymerase I with single-stranded DNA templates in vitro. GANP DNA-primase activity is controlled by phosphorylation at Ser(502) that is induced by CD40-mediated signaling in vitro and in the germinal center B cells stimulated with antigen in vivo. Overexpression of ganp cDNA in Daudi B cells caused the increased DNA synthesis more t |
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| Immunogen | n/a |
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| Other Names | Germinal-center associated nuclear protein; 80 kDa MCM3-associated protein; MCM3 acetylating protein; MCM3 acetyltransferase; MCM3AP; GANP; KIAA0572; MAP80 |
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| Gene, Accession # | Entrez: 294339, 54387, 8888; Uniprot: O60318, Q9WUU9 |
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| Catalog # | PA5-75166 |
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| Price | |
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| Order / More Info | GANP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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