| Edit |   |
| Antigenic Specificity | PYDC1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 400 µl |
| Concentration | n/a |
| Applications | Western Blot: 1:1000 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PYDC1 Polyclonal Antibody. ASC2 associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS. |
| Immunogen | n/a |
| Other Names | Pyrin domain-containing protein 1; PAAD-only protein 1; Pyrin-only protein 1; PYDC1; ASC2; ASCI; POP1; PYC1 |
| Gene, Accession # | Entrez: 260434; Uniprot: Q8WXC3 |
| Catalog # | PA5-71785 |
| Price | |
| Order / More Info | PYDC1 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |