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| Product Name | Recombinant Human HLA class II histocompatibility antigen, DP alpha 1 chain protein |
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| Description | 29-222aa; Extracellular Domain. MW: 26.4kD. Purity >90% as determined by SDS-PAGE. Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents th on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteas |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [DP(W3); DP(W4); HLA-SB alpha chain; MHC class II DP3-alpha; MHC class II DPA1] |
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| Gene, Accession, CAS # | HLA-DPA1, Gene ID: 3113, Accession: NP_001229453.1 |
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| Catalog # | MBS1265567 |
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| Order / More Info | Recombinant Human HLA class II histocompatibility antigen, DP alpha 1 chain protein from MYBIOSOURCE INC. |
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| Product Specific References | The genomic organisation and nucleotide sequence of the HLA-SB(DP) alpha gene.Lawrance S.K., Das H.K., Pan J., Weissman S.M.Nucleic Acids Res. 13:7515-7528(1985) Class II genes of the human major histocompatibility complex. Evolution of the DP region as deduced from nucleotide sequences of the four genes.Gustafsson K., Widmark E., Jonsson A.-K., Servenius B., Sachs D.H., Larhammar D., Rask L., Peterson P.A.J. Biol. Chem. 262:8778-8786(1987) Epitope recognition by a DP alpha chain-specific monocl |
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