| 产品详情 |
| Edit |   |
|---|
| Product Name | Halofuginone (hydrochloride) |
|---|
| Description | A halogenated derivative of febrifugine that down-regulates Smad3, blocking TGF-β signaling relevant to fibrosis and tumor progression in a variety of different models; competitively inhibits prolyl-tRNA synthetase (Ki = 18.3 nM), preventing the differentiation of TH17 cells and blunting an autoimmune response |
|---|
| Size | 5 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 55837-20-2 inhibitors inhibitions inhibits cancers genes regulations autoimmunity infectious diseases immunology HCl TGF-β TGF-.beta. TGF-beta TGF-b TGF β .beta. beta b signals signaling TH17 differentiation derivatives febrifugine D. D febrifuga antimalarial anti-malarial anti malarial malaria anticoccidial anti-coccidial coccidial Smad3 fibroblasts myofibroblasts epithelial cells mesenchymal fibrosis tumors competitive competitively prolyl-tRNA prolyl tRNA synthetase monohydrochloride autoimmune diseases |
|---|
| Gene, Accession, CAS # | CAS: 1217623-74-9 |
|---|
| Catalog # | 13370-5 |
|---|
| Price | |
|---|
| Order / More Info | Halofuginone (hydrochloride) from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|