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Product Name | Recombinant Human Eukaryotic translation initiation factor 3 subunit G (EIF3G) |
Description | Purity > 90% as determined by SDS-PAGE. MW: 51.5kDa. Full Length of Mature Protein: 2-320aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassbly and recycling of post-termination ribosomal complexes and subsequently prevents prature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Eukaryotic translation initiation factor 3 |
Gene, Accession, CAS # | EIF3G, UniProt: O75821 |
Catalog # | RPC21251 |
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Order / More Info | Recombinant Human Eukaryotic translation initiation factor 3 subunit G (EIF3G) from BIOMATIK |
Product Specific References | n/a |
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