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Product Name | Recombinant Human Eukaryotic translation initiation factor 3 subunit M (EIF3M) |
Description | Purity > 90% as determined by SDS-PAGE. MW: 58.4kDa. Full Length of Mature Protein: 2-374aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2). |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | eIF3m; Alternative name (s); Fetal lung protein B5; hFL-B5; PCI domain-containing protein 1 |
Gene, Accession, CAS # | EIF3M, UniProt: Q7L2H7 |
Catalog # | RPC20375 |
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Order / More Info | Recombinant Human Eukaryotic translation initiation factor 3 subunit M (EIF3M) from BIOMATIK |
Product Specific References | n/a |
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