| 产品详情 |
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| Product Name | Recombinant Human Exonuclease V (EXO5) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 57.8kDa. Full Length: 1-373aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage. Has both 5'-3' and 3'-5' exonuclease activities with a strong preference for 5'-ends. Acts as a sliding exonuclease that loads at ssDNA ends and then slides along the ssDNA prior to cutting; however the sliding and the 3'-5' exonuclease activities are abolished upon binding to the replication protein A (RPA) complex that enforces 5'-directionality activity. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Defects in morphology protein 1 homolog |
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| Gene, Accession, CAS # | EXO5, UniProt: Q9H790 |
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| Catalog # | RPC23557 |
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| Order / More Info | Recombinant Human Exonuclease V (EXO5) from BIOMATIK |
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| Product Specific References | n/a |
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