| 产品详情 |
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| Product Name | NVP-ACC789 |
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| Description | An inhibitor of VEGFRs (IC50s = 0.38, 0.02, 0.18, and 0.23 µM for human VEGFR1, 2, 3, and mouse Vegfr2, respectively); selective for VEGFRs over FGFRs and PDGFRα (IC50s = >10 µM), but has activity at PDGFRβ (IC50 = 1.4 µM) in an enzyme assay; inhibits VEGF-induced VEGFR2 autophosphorylation (IC50 = 11.5 nM in CHO cells transfected with the human receptor); blocks bFGF- and VEGF-induced angiogenesis (ED50s = 9 and 26 mg/kg, respectively) in a mouse model of growth factor-induced angiogenesis |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 393513-27-4 NVPACC789 ACC-789 AAC-789 ZK202650 ZK-202650 chinese hamster ovary AAC789 vascular endothelial VEGFR3 fibroblast platelet-derived PDGFR-α β PDGFRa PDGFRb VEGFR-2 3 |
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| Gene, Accession, CAS # | CAS: 300842-64-2 |
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| Catalog # | 23458-1 |
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| Price | |
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| Order / More Info | NVP-ACC789 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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