| 产品详情 |
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| Antigenic Specificity | AXIN1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 20 µg/mL, Immunohistochemistry: 20 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AXIN1 Polyclonal Antibody. AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of beta-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor. |
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| Immunogen | n/a |
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| Other Names | LA16c-314G4.3, AXIN, PPP1R49; axin-1; axis inhibition protein 1; axis inhibitor 1; fused, mouse, homolog of; protein phosphatase 1, regulatory subunit 49 |
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| Gene, Accession # | Entrez: 12005, 79257, 8312; Uniprot: O15169, O35625, O70239 |
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| Catalog # | PA5-21042 |
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| Price | |
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| Order / More Info | AXIN1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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