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Product Name | Notch-1, mouse recombinant |
Description | Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins. MW: ~85.0 kDa. The extracellular domain of mouse Notch-1 (aa 19-488) (12 epidermal growth factor-like (EGF) repeats) is fused at |
Size | 25 µg |
Concentration | n/a |
Applications | RUO |
Other Names | Neurogenic Locus Notch Homolog Protein 1; Notch A; mT14; p300 |
Gene, Accession, CAS # | NOTCH1, Gene ID: 18128, Accession: Q01705 |
Catalog # | 7530-25 |
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Order / More Info | Notch-1, mouse recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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