| 产品详情 |
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| Product Name | Recombinant Rat HER2 / ErbB2 Protein |
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| Description | MW: 138,832 Da. Purity >92 % as determined by SDS-PAGE. Background: Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand b |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | The recombinant rat ErbB2/Fc is a disulfide-linked homodimer. The reduced monomer comprises 638 amino acids and predicts a molecular mass of 70.6 kDa. The apparent molecular mass of the rat ErbB2 is approximately 95-105 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
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| Other Names | [ErbB2, Neu, p185erbB2] |
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| Gene, Accession, CAS # | HER2 / ErbB2, Gene ID: 24337, Accession: AAH61863.1 |
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| Catalog # | MBS2547473 |
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| Order / More Info | Recombinant Rat HER2 / ErbB2 Protein from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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