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| Product Name | Protein Carbonyl Content Assay Kit (Fluorometric) |
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| Description | Protein carbonylation occurs when chronically elevated blood sugar levels create a microenvironment for sugars to covalently react with amino acids forming non-enzymatic adducts. Oxidative stress, the excessive production of ROS, can also give rise to the production of protein carbonyls. Over time, these two processess create Advanced Glycation End-products (AGEs) with proteins. The major functional outcome of protein-reactive AGEs is reduced enzymatic activity. Soluble AGEs can also bind and activate the receptor of advanced glycation end-products (RAGE). Receptor-dependent outcomes lead to tissue dysfunction, oxidative stress, and activation of monocytes, endothelial cells and mesangial cells. In Alzheimer's Disease (AD) protein carbonyls |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | Quantification of carbonyl content as a putative biomarker for research in disease areas such as diabetes, multiple sclerosis, and Alzheimer's diseas |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K563-100 |
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| Order / More Info | Protein Carbonyl Content Assay Kit (Fluorometric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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