| 产品详情 |
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| Antigenic Specificity | DYRK2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DYRK2 Polyclonal Antibody. DYRK2, or dual specificity tyrosine-phosphorylation-regulated kinase 2, has a role in the regulation of cellular growth and/or development. In response to DNA damage, DYRK2 regulates p53 phosphorylation on Ser-46 to induce apoptosis. DYRK2 has been proposed to inactivate GYS1 by phosphorylation at Ser-641, and potentially a second phosphorylation site, thus regulating glycogen synthesis. DYRK2 also phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates. |
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| Immunogen | n/a |
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| Other Names | Dual specificity tyrosine-phosphorylation-regulated kinase 2, Dyrk2 |
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| Gene, Accession # | Entrez: 69181, 8445; Uniprot: Q5U4C9, Q92630 |
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| Catalog # | PA5-48658 |
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| Price | |
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| Order / More Info | DYRK2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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