| 产品详情 |
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| Antigenic Specificity | BRD7 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | ELISA: Assay-dependent, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BRD7 Polyclonal Antibody. BRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation. BRD7 promotes acetylation of TP53 at Lys-382, and thereby promotes efficient recruitment of TP53 to target promoters, inhibiting cell cycle progression from G1 to S phase. |
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| Immunogen | n/a |
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| Other Names | Bromodomain-containing protein 7, 75 kDa bromodomain protein, Protein CELTIX-1, BRD7, BP75, CELTIX1 |
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| Gene, Accession # | Entrez: 26992, 29117, 361374; Uniprot: O88665, Q9NPI1 |
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| Catalog # | PA5-78884 |
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| Price | |
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| Order / More Info | BRD7 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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