| 产品详情 |
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| Antigenic Specificity | CD117 (c-kit) |
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| Clone | A3C6E2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human CD117 (c-kit). CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemic cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117, and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells. The A3C6E2 antibody potently blocks the binding of SCF. |
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| Immunogen | MOLM-1 megakaryocitic cell line |
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| Other Names | C-kit, Stem cell factor receptor (SCF-R) |
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| Gene, Accession # | Gene ID: 3815 |
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| Catalog # | 323402 |
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| Price | |
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| Order / More Info | CD117 (c-kit) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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