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| Product Name | Recombinant Human Mitotic spindle assembly checkpoint protein MAD2A |
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| Description | 2-205aa; Full Length. MW: 39.36kD. Purity >90% as determined by SDS-PAGE. Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Mitotic arrest deficient 2-like protein 1; MAD2-like protein 1] |
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| Gene, Accession, CAS # | MAD2L1, Gene ID: 4085, Accession: NP_002349.1 |
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| Catalog # | MBS1380961 |
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| Order / More Info | Recombinant Human Mitotic spindle assembly checkpoint protein MAD2A from MYBIOSOURCE INC. |
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| Product Specific References | Identification of a human mitotic checkpoint gene hsMAD2.Li Y., Benezra R.Science 274:246-248(1996) Genomic structure of the human MAD2 gene and mutation analysis in human lung and breast cancers.Gemma A., Hosoya Y., Seike M., Uematsu K., Kurimoto F., Hibino S., Yoshimura A., Shibuya M., Kudoh S., Emi M.Lung Cancer 32:289-295(2001) Jin D.-Y., Jeang K.-T.Klebert S., Barnikol-Watanabe S., Kratzin H.D., Hilschmann N. Complete human MAD2 gene.Nobori T.Identifying a new variant of MAD2L1.Yin F., Fan |
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