| 产品详情 |
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| Product Name | Recombinant Human Mixed lineage kinase domain-like protein |
| Description | 1-471aa; Full Length. MW: 70.44kD. Purity >90% as determined by SDS-PAGE. Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity. |
| Size | 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (E-Coli), 0.1 mg (E-Coli) |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [mixed lineage kinase domain-like protein isoform 2; Mixed lineage kinase domain-like protein; mixed lineage kinase domain-like protein; mixed lineage kinase domain-like] |
| Gene, Accession, CAS # | MLKL, Gene ID: 197259, Accession: NP_001135969.1 |
| Catalog # | MBS1424763 |
| Price | |
| Order / More Info | Recombinant Human Mixed lineage kinase domain-like protein from MYBIOSOURCE INC. |
| Product Specific References | The protein kinase complement of the human genome.Manning G., Whyte D.B., Martinez R., Hunter T., Sudarsanam S.Science 298:1912-1934(2002) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Ya |
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