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Product Name | WM3670 Non-Viable Cell Pellet (Bulk) |
Description | Non-viable cell pellet was generated from cell line WM3670. WM3670 is a metastatic human melanoma cell line with epithelial morphology. This cell line features the G469E mutation at codon 469 in the BRAF gene. The G469E mutation results in an amino acid substitution at position 469 in BRAF, from a glycine (G) to a glutamic acid (E). This mutation occurs within the highly conserved GXGXXG motif of the kinase domain. Most mutant BRAF proteins have increased kinase activity and are transforming in vitro. This cell line contains a G12D mutation at position 12 in the N-RAS gene. The G12D mutation results in an amino acid substitution at position 12 in N-RAS, from a glycine (G) to an aspartic acid (D). |
Size | 1 each |
Concentration | n/a |
Applications | Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation. |
Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
Gene, Accession, CAS # | n/a |
Catalog # | WM3670-03-Bulk |
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Order / More Info | WM3670 Non-Viable Cell Pellet (Bulk) from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |
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