| 产品详情 |
| Edit |   |
|---|
| Product Name | WM3749 Non-Viable Cell Pellet (Bulk) |
|---|
| Description | Non-viable cell pellet was generated from cell line WM3749. WM3749 is a metastatic human melanoma cell line that displays a mesenchymal and dendritic morphology. This cell line was established from a metastatic tissue site in a 54-year-old female patient. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line also expresses PTEN loss of function including homozygous deletion, and is wild type for N-RAS, c-KIT, and CDK4. WM3749 cells produce xenograft tumors when injected into immunocompromised mice. |
|---|
| Size | 1 each |
|---|
| Concentration | n/a |
|---|
| Applications | Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation. |
|---|
| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | WM3749-03-Bulk |
|---|
| Price | |
|---|
| Order / More Info | WM3749 Non-Viable Cell Pellet (Bulk) from ROCKLAND IMMUNOCHEMICALS INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|