产品详情 |
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Product Name | WM3854 Non-Viable Cell Pellet (Bulk) |
Description | Non-viable cell pellet was generated from cell line WM3854. WM3854 is a human metastatic melanoma cell line that displays a mesenchymal morphology. This cell line was established from a heavily pigmented metastatic site (right upper flank of back) in a 64-year-old male with superficial and deep inguinal nodes forming a 3.0 cm mass. This cell line contains a Q61L mutation at position 61 in the N-RAS gene which causes increased signaling via the extracellular signal-regulated MAPK/ERK kinase pathways to enhance proliferation. This cell line is known to be wild type for BRAF, c-KIT and CDK4. WM3854 cells produce xenograft tumors when injected into immunocompromised mice. |
Size | 1 each |
Concentration | n/a |
Applications | Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation. |
Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
Gene, Accession, CAS # | n/a |
Catalog # | WM3854-03-Bulk |
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Order / More Info | WM3854 Non-Viable Cell Pellet (Bulk) from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |
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