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| Product Name | WM9 Non-Viable Cell Pellet (Bulk) |
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| Description | Non-viable cell pellet was generated from cell line WM9. WM9 is a human metastatic melanoma cell line that was established from a metastatic site (left axillary node) in a male patient. This cell line features the V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line also expresses PTEN hemizygous deletion, and is wild type for N-RAS, c-KIT, and CDK4. WM9 cells produce xenograft tumors when injected into immunocompromised mice. |
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| Size | 1 each |
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| Concentration | n/a |
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| Applications | Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation. |
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| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | WM9-03-Bulk |
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| Order / More Info | WM9 Non-Viable Cell Pellet (Bulk) from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | Dorothee Herlyn et al., In Vitro Properties of Human Melanoma Cells Metastatic in Nude Mice. Cancer Research (1990) v50 2296-2302. |
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