| 产品详情 |
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| Antigenic Specificity | Smad4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | 0.5 mg/ml |
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| Applications | Western blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Smad4 Antibody. Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-β and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities throµgh interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members. |
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| Immunogen | Synthetic peptide corresponding to amino acids residues around 281 of human Smad4 |
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| Other Names | DPC4, JIP, MADH4 |
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| Gene, Accession # | Gene ID: 4089, Accession: BAB40977 |
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| Catalog # | 3464-100 |
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| Price | |
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| Order / More Info | Smad4 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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