| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD45RB |
|---|
| Clone | MEM-55 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, African green, baboon, cynomolgus, rhesus |
|---|
| Isotype | IgG2b, κ |
|---|
| Format | Alexa Fluor® 594 conjugate |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | IHC-P |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Alexa Fluor® 594 anti-human CD45RB. CD45RB is a 180-240 kD single chain type I membrane glycoprotein. It is an exon 5 splice variant of the tyrosine phosphatase CD45. The CD45RB isoform is expressed on thymocytes, T cell subsets, B cells, monocytes/macrophages, granulocytes, and dendritic cells. CD45RB enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines. The MEM-55 antibody recognizes a silaidase-sensitive epitope of CD45. |
|---|
| Immunogen | Human thymocytes and T lymphocytes |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | Gene ID: 5788 |
|---|
| Catalog # | 310208 |
|---|
| Price | |
|---|
| Order / More Info | CD45RB Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|