| 产品详情 |
| Edit |   |
|---|
| Product Name | Human Inosine-5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Screening Assay Kit |
|---|
| Description | Inosine monophosphate dehydrogenase, IMPDH, (E.C. 1.1.1.205) is the rate-limiting enzyme in de novo guanine nucleotide biosynthesis and it is essential for lymphocyte proliferation. IMPDH oxidizes inosine 5'-monophosphate (IMP) to xanthine 5'-monophosphate (XMP) using NAD as a cofactor. It plays a critical role in cell growth and in the malignancy of some tumors such as pancreatic, colon and bladder cancers. IMPDH2 is the predominant isoform of IMPDH and is specifically linked to a wide range of cancers and lymphocyte proliferation. IMPDH is recognized as a validated target as antiviral, antiparasitic, antimicrobial, antileukemic and immunosuppressive agents. In BioVison's IMPDH inhibitor screening assay, IMP is oxidized by IMPDH producing |
|---|
| Size | 100 assays |
|---|
| Concentration | n/a |
|---|
| Applications | Screening/characterizing/studying IMPDH inhibitors/activators |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | K495-100 |
|---|
| Price | |
|---|
| Order / More Info | Human Inosine-5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Screening Assay Kit from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|