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| Product Name | Recombinant Scytonema varium Scytovirin |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 23.7kDa. Full Length: 1-95aa. N-terminal 6xHis-B2M-tagged. Schistosoma mansoni (Blood fluke). Has strong anti-HIV activity against T-tropic strains of HIV-1 and weaker activity against M-tropic strains of HIV-1. Inhibits HIV-1 fusion and infection of CD4 LTR beta-gal cells in vitro. Inhibits fusion of HIV infected CEM-SS cells with uninfected CEM-SS cells, and fusion of HIV-1 Env expressing HL2/3 cells with CD4 LTR beta-gal cells. Binds to HIV gp120, HIV gp160 and to a lesser extent HIV gp41. Binding to HIV gp120 is glycosylation dependent. Binds with high specificity to the tetrasaccharide Man-alpha-1,2-Man-alpha-1,6-Man-alpha-1,6-Man and also binds the higher-order oligosaccharides oligomannose 8 and oligomannose 9. Does not bind to monosaccharides, complex or hybrid N-linked oligosaccharides or chitin. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | UniProt: P86041 |
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| Catalog # | RPC22351 |
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| Order / More Info | Recombinant Scytonema varium Scytovirin from BIOMATIK |
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| Product Specific References | n/a |
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