产品详情 |
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Antigenic Specificity | SPFH2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat, human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB, IP, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-Rat SPFH2 polyclonal antibody for WB, IP, ICC. Erlin-2 (UniProt B5DEH2; also known as Endoplasmic reticulum lipid raft-associated protein 2, SPFH domain-containing protein 2, SPFH domain family member 2, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) is encoded by the Erlin2 (also known as RGD1309010, Spfh2) gene (Gene ID 290823) in rat species. Erlin2 (Spfh2) and the highly homologous Erlin1 (Spfh1) are ER proteins that hetero-oligomerize into a large complex of ?2 MDa. The erlin1/2 complex associates with inositol 1,4,5-trisphosphate (IP(3)) receptors on ER membrane and is responsible for recruiting RNF170 upon IP(3) receptor activation for subsequent ubiquitination-dependent receptor downregulation. |
Immunogen | KLH-conjugated linear peptide corresponding to the C-terminus of rat ERLIN-2/SPFH2. |
Other Names | n/a |
Gene, Accession # | Gene ID: 290823, UniProt: B5DEH2 |
Catalog # | CABT-B1841 |
Price | |
Order / More Info | SPFH2 Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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