| 产品详情 |
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| Product Name | UNC-2025 |
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| Description | MW: 476.66. Purity ≥98% by HPLC. UNC-2025 is a potent inhibitor of the tyrosine kinases Mer and Flt3 (IC50s = 0.74 and 0.80 nM; respectively). It less potently inhibits Axl and Tyro3 (IC50s = 14 and 17 nM; respectively) and a panel of related kinases. UNC2025 blocks colony formation of Mer- and Flt3-dependent tumor cell lines and inhibits Mer phosphorylation in bone marrow leukemia cells in vivo. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [(1R; 4R)-4- (2- (butylamino)-5- (4- ( (4-methylpiperazin-1-yl) methyl) phenyl)-7H-pyrrolo[2; 3-d]pyrimidin-7-yl) cyclohexanol; MRX-6313] |
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| Gene, Accession, CAS # | CAS: 1429881-91-3 |
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| Catalog # | MBS846403 |
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| Order / More Info | UNC-2025 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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