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| Product Name | Plumbagin |
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| Description | Anticancer agent. Induces G2/M cell cycle arrest and apoptosis in A549 cells through JNK-dependent p53 Ser15 phosphorylation; inhibits A549 and MDA-MD-231 tumour xenograft growth in nude mice. Promotes autophagic cell death in MDA-MB-231 and MCF-7 cells and inhibits Akt/mTOR signaling. Induces intracellular ROS generation in a PI 5-kinase-dependent manner. Also inhibits p300-mediated acetylation of p53. Purity 98%. MW (observed): 188.18 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-Hydroxy-2-methyl-1,4-naphthalenedione |
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| Gene, Accession, CAS # | CAS: 481-42-5 |
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| Catalog # | 4761/50 |
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| Price | |
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| Order / More Info | Plumbagin from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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