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| Antigenic Specificity | Nesprin 2 |
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| Clone | K20-478-5 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:500, Immunofluorescence: 1:500, Immunomicroscopy: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:2500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Nesprin 2 Monoclonal Antibody (K20-478-5). There are two genes encoding members of a new family of type II integral membrane proteins. Both are ubiquitously expressed, and tissue-specific alternative mRNA initiation and splicing generate at least two major isoforms of each protein, with the smaller isoforms being truncated at the N-terminus. These proteins are called nesprin-l and -2 for nuclear _envelope _spectrin repeat, as they are characterized by the presence of multiple, clustered spectrin repeats, bipartite nuclear localization sequences and a conserved C-terminal, single transmembrane domain. Transient transfection of EGFP-fusion expression constructs demonstrated their localization to the nuclear membrane with a novel C-terminal, T |
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| Immunogen | n/a |
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| Other Names | Nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; Protein NUANCE; Synaptic nuclear envelope protein 2; Syne-2; KIAA1011; NUA |
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| Gene, Accession # | Entrez: 23224; Uniprot: Q8WXH0 |
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| Catalog # | MA5-18075 |
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| Price | |
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| Order / More Info | Nesprin 2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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