| 产品详情 |
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| Antigenic Specificity | Ly49H |
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| Clone | 3D10 |
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| Host Species | Mouse |
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| Reactive Species | mouse |
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| Isotype | IgG1, κ |
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| Format | purified, azide-free |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IP, Block |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LEAF™ Purified anti-mouse Ly49H. Ly49H, also known as Cmv1 and Klra8, is a 28.3 kD protein. It is expressed on NK cells (but not on NKT cells) from C57BL/6 mice (but not Balb/c or DBA/2 mice). Expression of Ly49H has been associated with resistance to MCMV infection in C57BL/6 mice. Modulation of Ly49H expression by its antibody made MCMV-resistant C57BL/6 mice susceptible to infection. Unlike Ly49A, Ly49H lacks the ITIM (immunoreceptor tyrosine-based inhibitory motif) but has ITAM (immunoreceptor tyrosine-based activation motif), which is associated with DAP-12 (KARAP, killer cell activating motif). |
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| Immunogen | C1498-Ly49A/H transfectant |
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| Other Names | Klra8, Cmv1, Cmv-1 |
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| Gene, Accession # | Gene ID: 16639 |
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| Catalog # | 144703 |
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| Price | |
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| Order / More Info | Ly49H Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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