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| Product Name | Mouse Fibroblast Growth Factor 8 (FGF15) ELISA Kit |
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| Description | Hypercholesterolemia is a risk factor for estrogen receptor (ER)-positive breast cancers and is associated with a decreased response of tumors to endocrine therapies. Here, we show that 27-hydroxycholesterol (27HC), a primary metabolite of cholesterol and an ER and liver X receptor (LXR) ligand, increases ER-dependent growth and LXR-dependent metastasis in mouse models of breast cancer. The effects of cholesterol on tumor pathology required its conversion to 27HC by the cytochrome P450 oxidase C |
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| Size | 48-strip-wells, 96-strip-wells, 5x96-strip-wells, 10x96-strip-wells, |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [fibroblast growth factor 8; Fibroblast growth factor 8; fibroblast growth factor 8; fibroblast growth factor 8; Androgen-induced growth factor; AIGF; Heparin-binding growth factor 8; HBGF-8] |
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| Gene, Accession, CAS # | FGF15, Gene ID: 2253, NCBI: AAC50785.1 |
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| Catalog # | MBS285521 |
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| Order / More Info | Mouse Fibroblast Growth Factor 8 (FGF15) ELISA Kit from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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