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| Product Name | Recombinant Mouse Tumor necrosis factor (Tnf), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 35.7kDa. Extracellular Domain: 57-235aa. N-terminal 6xHis-SUMO-tagged. Mus musculus (Mouse). Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; Short name:TNF-a |
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| Gene, Accession, CAS # | Tnf, UniProt: P06804 |
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| Catalog # | RPC22142 |
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| Order / More Info | Recombinant Mouse Tumor necrosis factor (Tnf), partial from BIOMATIK |
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| Product Specific References | n/a |
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