| 产品详情 |
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| Antigenic Specificity | IL-23 p19 |
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| Clone | 26HCLC |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IL-23 p19 Antibody (26HCLC), ABfinity™ Rabbit Oligoclonal. IL-23 is a member of the IL-12 cytokine family which is produced by dendritic cells and other antigen presenting cells in the peripheral tissues. This cytokine is a heterodimer composed of an IL-12p40 subunit, and a p19 subunit. IL-23 plays an important role in stimulating memory T-cells. It is also required for the induction, expansion, maintenance, and downstream effector functions of Th17 cells. Th17 cells play a vital role in upregulating neutrophil chemokines and various pro-inflammatory cytokines. IL-23 interacts with the receptors IL-12R beta1 and IL-23R to activate the Jak-Stat signaling cascade. |
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| Immunogen | n/a |
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| Other Names | Interleukin 23, IL-23A, IL23P19, MGC79388, P19, SGRF |
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| Gene, Accession # | Entrez: 51561; Uniprot: Q9NPF7 |
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| Catalog # | 710259 |
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| Price | |
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| Order / More Info | IL-23 p19 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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