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Antigenic Specificity | Prostaglandin E Receptor EP1/PTGER1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted: hamster) |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100ug (sample available) |
Concentration | 500ug/ml. |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Prostaglandin E2 receptor EP1 subtype(PTGER1) detection. Tested with WB in Human. No cross reactivity with other proteins. PTGER1, Prostaglandin E Receptor 1, comprises 402 amino acids with a predicted molecular mass of 41, 858 and has the 7 predicted transmembrane-spanning domains common to all G protein-coupled receptors. The PTGER1 gene is mapped to chromosome 19p13.1. The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2(PGE2). Through a phosphatidylinositol-calcium second messenger system, Gq proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. |
Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Prostaglandin E Receptor EP1(387-404aa AWEASSLRSSRHSGLSHF). |
Other Names | Prostaglandin E2 receptor EP1 subtype;PGE receptor EP1 subtype;PGE2 receptor EP1 subtype;Prostanoid EP1 receptor;PTGER1; |
Gene, Accession # | PTGER1, UniProt: P34995 |
Catalog # | PA1583 |
Price | |
Order / More Info | Prostaglandin E Receptor EP1/PTGER1 Antibody from BOSTER BIO |
Product Specific References | n/a |