| 产品详情 |
| Edit |   |
|---|
| Product Name | MGL-3196 |
|---|
| Description | An agonist of TRβ (EC50s = 0.21 and 3.74 µM for TRβ and TRα, respectively); inhibits hERG channels (IC50 = 30 µM); liver-directed, with a liver to plasma ratio of 8:1 to reduce systemic exposure; does not affect the expression of α-MHC in a rat model of hypothyroidism, an effect mediated by TRα; lowers non-HDL cholesterol and liver triglycerides without affecting Tsh levels in rat and rabbit models of hypercholesterolemia; lowers plasma glucose levels and improves insulin sensitivity in DIO mice |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | MGL3196 VIA3196 TRa TRb aMHC VIA-3196 αMHC high density lipoprotein nonalcoholic |
|---|
| Gene, Accession, CAS # | CAS: 920509-32-6 |
|---|
| Catalog # | 23845-10 |
|---|
| Price | |
|---|
| Order / More Info | MGL-3196 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|