| 产品详情 |
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| Antigenic Specificity | ARRB1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 ul |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit polyclonal to ARRB1.Beta-arrestin-1 (ARRB1) is a cytosolic protein that belongs to the arrestin family. Beta arrestinsfunction in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediatingboth receptor desensitization and resensitization processes. It is involved in IL8-mediated granulerelease in neutrophils. Beta-arrestin-1 acts as a cofactor in the beta-adrenergic receptor kinase(BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, itis expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system isbelieved to play a major role in regulating receptor-mediated immune functions. |
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| Immunogen | N-terminal region of human ARRB1 |
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| Other Names | ARRB1,Betaarrestin1,Arrestin beta1,ARR1 |
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| Gene, Accession # | UniProt: P49407 |
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| Catalog # | orb67279 |
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| Price | |
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| Order / More Info | ARRB1 Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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